Polymerase chain reaction (PCR) for detection superantigenicity of Staphylococcus aureus isolated from psoriatic patients

Abstract

Enterotoxigenic Stapylococcus aureus has an important role in triggering and maintenance psoriasis.
This study was done to identify the frequency of the, genetic basis, enterotoxigenc S. aureus in
psoriatic patient. Polymerase chain reaction (PCR) was performed for detect S. aureus enterotoxine A
and B genes of bacteria isolated from psoriatic patients. S. aureus of psoriatic skin lesions have the
enterotoxin genes (55%) significantly more than those from healthy skin of psoriatic patients (10%).
Two genes were examined to be harbored by S. aureus isolates, namely enterotoxin A gene (22.5%) and
enterotoxin B gene (10%) from psoriatic lesions, versus 10% of isolates from healthy skin of psoriatic
patients that harbored enterotoxin B gene only. Enterotoxigenic S. aureus (A and B genes) isolated
from psoriatic patients have an associated role with psoriatic lesions.