Studied Chinese herbs on Helicobacter pylori

Authors

  • Ming-yu Li
  • Jun Wang
  • Zhu-ting Xu

Keywords:

Chinese herbs, extract, Helicobacter pylori, comparative study, activity.

Abstract

Helicobacter pylori (H. pylori) are a bacterium implicated in the etiology of stomach cancer and ulcers.
Epidemiology of the antibiotic resistance of H. pylori appears to be higher. The study was to screen an
efficiency substance of Chinese herbs, which could be used in preventing and treating H. pylori
diseases. A total of 40 extracted efficiency substances from Chinese herbs were examined and screened
for anti-H. pylori activity performed on 96 microwell plate. 45 cases of chronic gastritis with H. pylori
infected were treated by a prescription based on Chinese herbs of “clear heat and eliminate toxins”. It is
showed that all except 15 extract from 40 plants were identified as having potent anti-H. pylori activities.
But the most active extracts were those from Gallnut (cocoon) of Chinese Sumac (MIC: <1:512), Clover
Flower Bud (MIC: 1:256), Houtuynia (MIC: 1:512), Agrimony (MIC: 1:256) Coptis Rhizome (MIC: <1:512).
Subsequently, a detailed comparative study of the extract of the active herbs was performed to anti-H.
pylori. Amongst the active plants the inhibitory properties of H. pylori were found prominent. Gallnut
(cocoon) of Chinese Sumac, Clover

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Published

2012-11-13