Enhancing riboflavin production through seawater-derived Candida tropicalis

Abstract

Screening of Candida spp. capable of riboflavin production from seawater samples in Chonburi province was
conducted. Total of 47 isolates were identified as Candida tropicalis and Candida krusei with similar
percentages of distribution. Among those identified isolates, only two of C. tropicalis, MICBUU002 and
MICBUU019, were found to be able to produce riboflavin with concentrations of 254.22 ± 5.51 and 199.53 ± 0.74
ug/ml, respectively, on day-5 of incubation at 30°C in a medium broth containing 2% glucose as a sole carbon
source. In contrary, none of C. krusei isolates showed the capability to produce riboflavin. The results implied
that the capability of C. tropicalis to produce riboflavin was not an exclusive property of this specie since not
every isolates of this Candida had this capability, at least at the detectable level that could be measured.