Phylogenetic and pathogenetic analysis of Streptococcus suis serotype 7 strain HW07 isolated from diseased pig in China

Authors

  • Shujie Wang, Sen Hu , Jiamin Jin, Yonggang Liu , Gang Wang , Yabin Tu , Chenggang Jiang , Xuehui Cai, Xiuying Zhang

Keywords:

Streptococcus suis serotype 7, multilocus sequence typing, the sequence type, phylogenetic analysis

Abstract

A recent isolate of Streptococcus suis serotype 7 (SS7), named HW07, was isolated from brains of pigs
suspected with Streptococcus suis (S. suis) infection. The sequence types (ST) of this isolate was determined
by Multilocus sequence typing (MLST) method. In order to evaluate pathogenesis of HW07 isolate, zebrafish
and pigs were inoculated with HW07 strain by peritoneal cavity and vein. The results demonstrate that the 50%
lethal dose (LD50) of HW07 isolate was 1.25 × 105
colony forming units (CFU)/fish and could induce pig
disease, the ST number of HW07 isolate is a novel ST-ST335. Molecular and phylogenetic analysis for the recA
gene of HW07 isolate showed that it joins to the I group cluster of S. suis strains, the predominant genotype in
China.

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Published

2020-01-08

How to Cite

Shujie Wang, Sen Hu , Jiamin Jin, Yonggang Liu , Gang Wang , Yabin Tu , Chenggang Jiang , Xuehui Cai, Xiuying Zhang. (2020). Phylogenetic and pathogenetic analysis of Streptococcus suis serotype 7 strain HW07 isolated from diseased pig in China. African Journal of Pig Farming, 8(1), 1–7. Retrieved from https://elixirpublishers.in/index.php/ajpf/article/view/794

Issue

Vol. 8 No. 1 (2020): Volume 8 2020

Section

Articles