Molecular cloning and phylogenetic analysis of the E gene of transmissible gastroenteritis virus (TGEV) isolated in China

Authors

  • D. L. Lan, J. P. Gu, R. Xing, C. L. Yuan, L. Cui, X. G. Hua
  • Z. B. Yang

Keywords:

Transmissible gastroenteritis virus, E gene, phylogenetic analysis

Abstract

Porcine transmissible gastroenteritis caused by transmissible gastroenteritis virus (TGEV) induces acute,
high-contact intestinal infectious diseases in pigs. TGEV encodes four structural proteins including spike
(S), membrane (M), envelope (E) and nucleoprotein (N), of these, the genes of S, M and N respectively had
been deeply elucidated. However, the real function of E protein was still unclear and sequence
comparison of the E gene of different TGEV isolates had not been reported so far. In this study, E gene of
TGEV strain isolated in China was molecularly cloned and sequenced. Phylogenetic analysis confirmed
this gene was relatively conserved. All the China TGEV strains were brached in one clade together with
the American strains, but showed relatively alien to the European strains

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Published

2020-10-15

How to Cite

D. L. Lan, J. P. Gu, R. Xing, C. L. Yuan, L. Cui, X. G. Hua, & Z. B. Yang. (2020). Molecular cloning and phylogenetic analysis of the E gene of transmissible gastroenteritis virus (TGEV) isolated in China. African Journal of Pig Farming, 8(1), 1–4. Retrieved from https://elixirpublishers.in/index.php/ajpf/article/view/790

Issue

Vol. 8 No. 1 (2020): Volume 8 2020

Section

Articles