In-silico analysis of Mycobacterium leprae genome to find out potential drug targets

Abstract

Mycobacterium leprae is the causative agent of the disease, leprosy. In-silico analysis can be performed on M. leprae genome to find out the potential drug targets. This was done first by database search to find the recorded complete genes with complete sequences of M. leprae and then their comparative study with human by using homology searching using human BLAST. From a total of 1605 genes, potential drug targets have been identified.